Biolevox HA 2.2% 44mg

Biolevox HA 2.2% is a hyaluronic acid (HA) gel designed for intra-articular injection to alleviate symptoms of osteoarthritis (OA) in synovial joints. Each 2 ml pre-filled syringe contains 44 mg of sodium hyaluronate, providing an optimal 2.2% concentration.

Key Features

• High Molecular Weight Hyaluronate: Ranges from 1.4 to 2.4 MDa, ensuring optimal viscosity and elasticity for effective joint lubrication and shock absorption.
• Proven Efficacy: Clinical studies indicate that three consecutive weekly injections can reduce OA symptoms for at least six months.
• Convenient Packaging: Supplied in a sterile, ready-to-use 2 ml pre-filled syringe for easy administration.

Indications

Biolevox HA 2.2% is intended for patients experiencing pain and limited joint mobility due to post-traumatic or degenerative changes, such as osteoarthritis, in large joints like the knee, hip, and shoulder.

Administration

The recommended regimen consists of three intra-articular injections, each administered one week apart. This treatment plan has been shown to provide symptom relief for a minimum of six months. If necessary, the therapy cycle can be repeated.

Contraindications

• Known hypersensitivity to any of the product's components.
• Presence of septic arthritis or skin infections at the injection site.
• Patients undergoing anticoagulant therapy.
• Not recommended for use in children, pregnant, or breastfeeding women due to insufficient clinical data.

Precautions

• Ensure aseptic conditions during administration to prevent infections.
• For intra-articular use only; avoid intravascular injection.
• Do not use disinfectants containing quaternary ammonium salts, as they may cause hyaluronate precipitation.
• Inspect the pre-filled syringe for damage before use; do not use if compromised.
• Do not re-sterilize or reuse the syringe; it is intended for single use only.

Possible Side Effects

Some patients may experience temporary symptoms at the injection site, including:

• Pain
• Redness
• Swelling

These symptoms can often be alleviated by applying a cold compress for 5-10 minutes post-injection. Consult a healthcare professional if side effects persist or worsen.

Storage

• Store at temperatures between 2°C and 25°C.
• Protect from moisture and direct sunlight.
• Keep out of reach of children.

Composition

Each 1 ml of Biolevox HA 2.2% contains:

• Sodium hyaluronate: 22.000 mg
• Sodium chloride: 8.500 mg
• Disodium hydrogen phosphate: 0.563 mg
• Sodium dihydrogen phosphate: 0.045 mg
• Water for injection: q.s.

For more detailed information, please refer to the product's official documentation or consult a healthcare professional.